Uses: Sleeping Aid
Chemical Name: Zolpidem Tartrate
Quantity: 30 Tabs
WHAT IS ADCO-ZOPIMED?
Zopiclonebelongs to the group of medicines called central nervous system (CNS) depressants (medicines that make you drowsy or less alert). Adco-Zopimed is used to treat insomnia (trouble in sleeping). Adco-Zopimed helps you get to sleep faster and sleep through the night. In general, when sleep medicines are used every night for a long time, they may lose their effectiveness. In most cases, sleep medicines should be used only for short periods of time, such as 1 or 2 days, and generally for no longer than 1 or 2 weeks.
Adco-Zopimed is available only with your doctor's prescription.
ADCO-ZOPIMED INDICATIONS
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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In the treatment of transient, situational and chronic insomnia.
In the case of situational transient insomnia, such as in shift workers, short-term treatment (3-7 days) with Adco-Zopimed at the recommended dosage will be sufficient to re-establish normal sleep.
In insomnia secondary to psychiatric disorders including difficulty in falling asleep, nocturnal awakenings, and early wakening.
Insomnia caused by more persisting life stress or psychological distress can demand longer treatment with Adco-Zopimed than for situational - transient insomnia. However patients need to be periodically assessed for their insomnia and treatment should not be prolonged if not necessary.
USES OF ADCO-ZOPIMED IN DETAILS
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
Adco-Zopimed is used to treat insomnia (inability to sleep) in adults, including difficulty in falling asleep, waking in the night or too early in the morning, severe problems of sleep due to mood or mental health problems.
ADCO-ZOPIMED DESCRIPTION
Novo-Adco-Zopimed is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to Adco-Zopimed's benzodiazepine pharmacological properties it also has some barbiturate like properties
ADCO-ZOPIMED INTERACTIONS
Adco-Zopimed also interacts with trimipramine and caffeine. Alcohol has an additive effect when combined with Adco-Zopimed, enhancing the adverse effects including the overdose potential of Adco-Zopimed significantly. A study assessing the impact of Adco-Zopimed on driving skills the next day found that the impairments on driving skills are double that of a social dose of alcohol. Zaleplon had no detrimental effects on driving skills the next day. Carbamazepine also has additive effects when combined with Adco-Zopimed with both drugs enhancing the side effects of each other. Erythromycin appears to increase the absorption rate of Adco-Zopimed and prolong the elimination half life of Adco-Zopimed leading to increased plasma levels and more pronounced effects. Itraconazole has a similar effect on Adco-Zopimed pharmacokinetics as erythromycin. The elderly may be particularly sensitive to the erythromycin and itraconazole drug interaction with Adco-Zopimed. Temporary dosage reduction during combined therapy may be required especially in the elderly. Rifampicin causes a very notable reduction in half life of Adco-Zopimed and peak plasma levels which results in a large reduction in the hypnotic effect of Adco-Zopimed. Phenytoin and carbamazepine may also provoke similar interactions. Ketoconazole and sulfaphenazole interfere with the metabolism of Adco-Zopimed. Nefazodone impairs the metabolism of Adco-Zopimed leading to increased Adco-Zopimed levels and marked next day sedation.
ADCO-ZOPIMED SIDE EFFECTS
The side effect most commonly seen in clinical trials is taste alteration or dysgeusia (bitter, metallic taste, which is usually fleeting in most users but can persist until the drug’s half-life has expired). Palpitations may occur in the daytime following withdrawal from the drug after prolonged periods of use (especially when taken for more than two weeks).
Adco-Zopimed induces amnesia type memory impairments similar to triazolam and Rohypnol. Impairment of driving skills with a resultant increased risk of road traffic accidents is probably the most important side effect. This side effect is not unique to Adco-Zopimed but also occurs with other hypnotic drugs.
More common reactions
Gastrointestinal: taste disturbances including bitter metallic taste, dry mouth. Nervous system: disruption of REM sleep, double vision, drowsiness, memory impairments, visuospatial impairments, dizziness, headaches, and fatigue. Unexpected mood changes have been noted, which if experienced should lead to the drug being withdrawn from the patient.
Less common reactions
Gastrointestinal: heartburn, constipation, diarrhoea, nausea, coated tongue, bad breath, anorexia or increased appetite, vomiting, epigastric pains, dyspepsia, dehydration, parageusia.
Cardiovascular: palpitations in elderly patients.
Skin: urticaria, tingling in the arms and legs.
Miscellaneous: blurred vision, frequent micturition, mild to moderate increases in serum transaminases and/or alkaline phosphatase and interstitial nephritis have been reported very rarely.
Reproductive: impotence, delayed ejaculation, anorgasmia in both women and men.[citation needed]
Nervous system: agitation, anxiety, loss of memory including retrograde and anterograde amnesia, confusion, dizziness, weakness, somnolence, asthenia, moderate to severe euphoria and/or dysphoria, feeling of drunkenness, depression, sleep walking, coordination abnormality, hypotonia, speech disorder, hallucinations of various strengths, usually auditory and visual, behavioural disorders, aggression, tremor, rebound insomnia, nightmares, hypomania. Delirium can also occur but is a side effect mainly seen in the elderly.[26
ADCO-ZOPIMED CONTRAINDICATIONS
Adco-Zopimed causes impaired driving skills which are similar to benzodiazepines. Long term users of hypnotic drugs for sleep disorders only develop partial tolerance to adverse effects on driving with users of hypnotic drugs even after 1 years use still showing an increased motor vehicle accident rate. Patients who drive motor vehicles should not take Adco-Zopimed unless they stop driving due to a significant increased risk of road traffic accidents in Adco-Zopimed users. Adco-Zopimed induces impairment of psychomotor function. Driving or operating machinery should be avoided after taking Adco-Zopimed as effects can carry over to the next day including impaired hand eye coordination. Patients with a history of substance abuse should not be prescribed Adco-Zopimed, as it has a very high potential for problematic drug misuse. Adco-Zopimed is known to, in some case, induce a state of amnesia, which is largely related (and not too dissimilar to ’sleep-walking’).
