Nutrobal (MK-677 / Ibutamoren) – Info & Protocol
What it is
MK-677 is an oral growth hormone secretagogue.
It increases GH and IGF-1 by mimicking ghrelin.
Not a steroid, not suppressive to testosterone.
Main benefits
Improved sleep quality & recovery
Increased appetite (can be a pro or con)
Better skin, hair, joints
Gradual lean mass and strength support
May help fat loss indirectly via recovery/metabolism
Dosing Protocol (tablets are 10 mg each)
Beginner / conservative
10 mg daily
Take before bed (reduces hunger sides, improves sleep)
Standard / most common
20 mg daily
Either:
20 mg before bed OR
10 mg AM + 10 mg PM (if hunger is manageable)
Advanced (not always necessary)
25 mg daily max
Higher doses = more water retention & appetite
⏱ Half-life: ~24 hours → once daily is enough
Cycle Length
12–24 weeks (works best long-term)
Some run it year-round at 10–20 mg
No PCT required
Stacking
Works well with:
TRT or Test cycles
Peptides (CJC-1295, Ipamorelin)
Fat loss phases (monitor hunger closely)
Bulking phases (excellent appetite support)
Common Side Effects (dose dependent)
Increased appetite
Water retention / bloating
Mild lethargy initially
Possible insulin sensitivity reduction (important)
Reduce sides by:
Taking it at night
Keeping carbs cleaner
Adding berberine or metformin if needed
Staying hydrated & managing sodium
Important Notes (very relevant to you)
MK-677 can slightly raise blood glucose
Can increase T4 → T3 conversion demands
If you already have thyroid issues, monitor TSH/T4/T3
If using GLP-1s (semaglutide/tirzepatide):
MK-677 appetite increase may counter GLP-1 effect
Use lower dose (10–15 mg) or night-only dosing
Who should avoid or be cautious
Uncontrolled diabetes
Severe insulin resistance
Active cancer
Untreated thyroid dysfunction
Summary (best practical setup)
Dose: 10–20 mg
Timing: Night
Cycle: 16–24 weeks
Goal: Recovery, sleep, skin, lean mass support
If you want, tell me:
Your goal (fat loss vs muscle)
Whether you’re on GLP-1s or thyroid meds
Male/female & age
