Uses: Pain Relief and Anti inflammatory
Quantity: 1 x 2ml Vial
Chemical Name: Betamethasone
What is Celestone Soluspan and how is it used?
Celestone Soluspan is a prescription medicine used to treat the symptoms of Tenosynovitis, Peritendinitis, Bursitis (except on the foot), Rheumatoid Arthritis/Osteoarthritis, Multiple Sclerosis and Dermatologic. Celestone Soluspan may be used alone or with other medications.
Celestone Soluspan belongs to a class of drugs called Corticosteroids; Immunosuppressives, PHD.
What are the possible side effects of Celestone Soluspan?
Celestone Soluspan may cause serious side effects including:
fast, slow or irregular heartbeats,
blurred vision,
tunnel vision,
eye pain,
seeing halos around lights,
bumps on the skin,
raised blotches (purple, pink, brown or red) on the skin,
chest pain,
swollen glands,
seizure,
swelling,
rapid weight gain,
shortness of breath,
pain and swelling or stiffness in your joints with fever,
general ill feeling,
severe pain in your upper stomach spreading to your back,
severe depression,
changes in personality,
unusual thoughts or behavior,
weight gain in your face and shoulders,
slow wound healing,
skin discoloration,
thinning skin,
increased body hair,
tiredness,
mood changes,
growth (in children),
menstrual changes, and
sexual changes
Get medical help right away, if you have any of the symptoms listed above.
The most common side effects of Celestone Soluspan include:
headache,
depression,
mood swings,
sleep problems (insomnia),
numbness,
tingling,
burning pain,
skin redness,
itching,
skin discoloration,
thinning skin,
stretch marks,
muscle weakness,
nausea,
bloating, and
stomach pain
Tell the doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Celestone Soluspan. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
DESCRIPTION
CELESTONE® SOLUSPAN® Injectable Suspension is a sterile aqueous suspension containing 3 mg per milliliter betamethasone, as betamethasone sodium phosphate, and 3 mg per milliliter betamethasone acetate. Inactive ingredients per mL: 7.1 mg dibasic sodium phosphate anhydrous or 8.9 mg dibasic sodium phosphate dihydrate; 3.4 mg monobasic sodium phosphate monohydrate or 3.8 mg monobasic sodium phosphate dihydrate; 0.1 mg edetate disodium; and 0.2 mg benzalkonium chloride as preservative. The pH is adjusted to between 6.8 and 7.2.
The formula for betamethasone sodium phosphate is C22H28FNa208P and it has a molecular weight of 516.40. Chemically, it is 9-Fluoro-11β,17,21-trihydroxy-16βmethylpregna- 1,4-diene-3,20-dione 21-(disodium phosphate).
The formula for betamethasone acetate is C24H31FO6 and it has a molecular weight of 434.50. Chemically, it is 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene3,20- dione 21-acetate.
The chemical structures for betamethasone sodium phosphate and betamethasone acetate are as follows:
Betamethasone sodium phosphate is a white to practically white, odorless powder, and is hygroscopic. It is freely soluble in water and in methanol, but is practically insoluble in acetone and in chloroform.
Betamethasone acetate is a white to creamy white, odorless powder that sinters and resolidifies at about 165°C, and remelts at about 200°C-220°C with decomposition. It is practically insoluble in water, but freely soluble in acetone, and is soluble in alcohol and in chloroform.
INDICATIONS
When oral therapy is not feasible, the intramuscular use of CELESTONE® SOLUSPAN® Injectable Suspension is indicated as follows:
Allergic States
Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, perennial or seasonal allergic rhinitis, serum sickness, transfusion reactions.
Dermatologic Diseases
Bullous dermatitis herpetiformis, exfoliative erythroderma, mycosis fungoides, pemphigus, severe erythema multiforme (Stevens-Johnson syndrome).
Endocrine Disorders
Congenital adrenal hyperplasia, hypercalcemia associated with cancer, nonsuppurative thyroiditis.
Hydrocortisone or cortisone is the drug of choice in primary or secondary adrenocortical insufficiency. Synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy mineralocorticoid supplementation is of particular importance.
Gastrointestinal Diseases
To tide the patient over a critical period of the disease in regional enteritis and ulcerative colitis.
Hematologic Disorders
Acquired (autoimmune) hemolytic anemia, Diamond-Blackfan anemia, pure red cell aplasia, selected cases of secondary thrombocytopenia.
Miscellaneous
Trichinosis with neurologic or myocardial involvement, tuberculous meningitis with subarachnoid block or impending block when used with appropriate antituberculous chemotherapy.
Neoplastic Diseases
For palliative management of leukemias and lymphomas.
Nervous System
Acute exacerbations of multiple sclerosis; cerebral edema associated with primary or metastatic brain tumor or craniotomy.
